Upcon® – Upconverting Nanoparticle System
Upcon is a comprehensive concept built around a novel label technology based on photon upconversion. Upconverting nanoparticles (UCNPs) provide several advantages over traditional fluorescent labels like conventional fluorophores or quantum dots. In this unique detection technology, near-infrared excitation (980 nm) is converted to visible light via a process that totally eliminates autofluorescence and scattered excitation light. The Upcon® nanoparticles are bright and photostable and very well suited for use in quantitative lateral flow (LF) assays, for example.
Our nanoparticle offering
Upcon® nanoparticles are available as functionalized (e.g. COOH) or as biomolecule conjugates (e.g. conjugated to streptavidin or an antibody of your choice). We offer a conjugation service and an assay development service, and we can also help you to evaluate the technology in your own assay. Several options are available regarding the nanoparticle size and coating (which is fundamental in rendering the nanoparticles hydrophilic). Some options are already manufactured under ISO 13485 and more are in the R&D pipeline.